The therapeutic index (TI; also referred to as therapeutic ratio) is a quantitative measurement of the relative safety of a drug.It is a comparison of the amount of a therapeutic agent that causes the therapeutic effect to the amount that causes toxicity. The related terms therapeutic window or safety window refer to a range of doses which optimize between efficacy and toxicity, achieving the ...Therapeutic effect refers to the response(s) after a treatment of any kind, the results of which are judged to be useful or favorable. This is true whether the result was expected, unexpected, or even an unintended consequence.An adverse effect (including nocebo) is the converse and refers to harmful or undesired response(s).What constitutes a therapeutic effect versus a side effect is a ...
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